Duo-Layer Resurfacing, iMedPen® Microneedling with PDRN
Advanced Regenerative Skin Correction is a clinically designed skin regeneration treatment that combines Toskani Duosomal resurfacing with iMedPen® microneedling and regenerative PDRN (Polydeoxyribonucleotide) infusion to improve skin quality, texture, resilience, and overall skin function. This treatment has been developed to stimulate controlled renewal and regenerative activity within the skin through measured correction rather than aggressive exfoliation or excessive trauma.
The skin correction treatment begins with Toskani Duosomal resurfacing, an advanced dual-delivery acid system designed to stimulate epidermal renewal in a progressive and controlled manner. Unlike conventional peels that rely on excessive surface aggression, Duosomal technology combines liposomal-encapsulated acids with free acids to create a layered response within the skin. The encapsulated acids support progressive and controlled delivery within the skin to encourage renewal while helping minimise unnecessary irritation, while the free acids work more superficially to refine, brighten, and improve visible skin clarity. This allows effective resurfacing without excessive inflammation, significant peeling, or prolonged downtime. The specific Duosomal formulation selected is tailored according to your skin presentation, whether the focus is dullness, congestion, pigmentation irregularities, dehydration, barrier dysfunction, or early structural ageing.
Following resurfacing, microneedling is performed with the professional iMedPen® to encourage collagen signalling, stimulate regenerative activity, and enhance delivery of active ingredients into the skin. Needle depth is kept conservative and controlled within the superficial skin layers, ensuring the treatment focuses on stimulation and regeneration rather than excessive trauma. This stage of the treatment helps improve skin texture, refine overall skin quality, and support natural repair processes associated with collagen and elastin production.
During microneedling, a sterile medical-grade PDRN solution is infused into the skin to further support tissue repair and regenerative activity. PDRN, derived from highly purified salmon DNA fragments, works by supporting fibroblast activity, promoting cellular repair pathways, regulating inflammatory responses, and improving overall skin recovery and function. When combined with microneedling, PDRN delivery supports collagen production, hydration, elasticity, skin resilience, and dermal quality while reducing visible inflammation and supporting recovery following treatment. This regenerative approach is particularly beneficial for dull, dehydrated, thinning, environmentally stressed, or ageing skin, as well as skin presenting with fine lines, uneven texture, superficial acne scars, mild pigmentation concerns, or compromised barrier function.
By combining controlled resurfacing with regenerative microneedling-assisted PDRN delivery, this treatment works both at the surface and within the superficial dermal environment to improve overall skin performance, rather than creating only temporary cosmetic change. Skin gradually appears smoother, brighter, firmer, healthier, and more resilient as regenerative processes continue over the following weeks.
Following microneedling, a regenerative calming mask is applied to help reduce visible redness, support hydration, calm post-treatment heat, and reinforce barrier recovery while the skin begins its regenerative repair processes. This final stage of the treatment helps optimise skin comfort, minimise unnecessary inflammatory stress, and support overall recovery following resurfacing and microneedling. The selected mask is chosen based on your skin presentation and may focus on hydration support, barrier reinforcement, calming inflammation, or enhancing regenerative recovery, depending on the skin’s needs at the time of treatment.
Following treatment, mild pinkness and warmth may persist for approximately 24 to 48 hours. Temporary tightness or dryness may occur as the skin undergoes controlled renewal, although significant peeling is not typically expected; some peeling may occur. Comprehensive aftercare guidance will be provided to support skin recovery and optimise treatment outcomes.
A course of three treatments, spaced approximately 4 weeks apart, is recommended for visible corrective improvement and progressive skin regeneration. Ongoing maintenance treatments may be advised depending on individual skin presentation and long-term skin goals.
This treatment is ideal for those seeking a structured, consultation-led regenerative skin treatment that improves overall skin quality, function, and long-term skin health, without the downtime associated with more aggressive resurfacing procedures.

