HYPO21 Purifying Skin Spray is a cosmetically licensed hypochlorous acid (HOCl) formulation that is registered with the Medicines and Healthcare products Regulatory Agency (MHRA) as a medical device. It carries both MD and UKCA certification, confirming compliance with European regulatory standards for safety, quality, and performance. This positions HYPO21 as a clinically aligned HOCl solution suitable for at-home use within skin health management.

The formulation of  HYPO21 Purifying Skin Spray is suitable for all skin conditions, including sensitive, chronic, and reactive skin. Using water and salt, the solution is produced through a controlled electrolytic process to generate pure hypochlorous acid at a stable, skin-compatible pH. This ensures efficacy while minimising the risk of irritation. The formulation does not contain sodium hypochlorite, alcohol, or any additional sensitising agents; it is in its pure form. It is free from parabens, sulphates, phthalates, silicones, formaldehyde, aluminium, microplastics, and synthetic fragrance, supporting its use across all compromised skin presentations.

In early 2025, the HYPO21 range, including the purifying skin spray, oral rinse, and baby and nappy care products, received approval from the U.S. Food and Drug Administration. This confirms that the products meet recognised standards for safety, efficacy, and manufacturing quality within the United States regulatory framework.

Hypochlorous acid (HOCl) is a substance the body naturally produces as part of its immune system. It is made by white blood cells to help protect against infection and support the healing of damaged skin. When applied to the skin, HOCl acts as a broad-spectrum antimicrobial, reducing bacteria, viruses, fungi, mites and other harmful microbes. At the same time, it is gentle and does not damage healthy skin cells, which makes it suitable for regular use, even on sensitive, inflamed, or compromised skin.

Clinically, HYPO21 Purifying Skin Spray is used to support a wide range of skin conditions and presentations. Some of these conditions include (but are not limited to): all grades of acne, rosacea, eczema, psoriasis, seborrhoeic dermatitis, atopic dermatitis, and perioral dermatitis. It is also suitable for use on acute and chronic wounds, including cuts, ulcers (including diabetic ulcers), abrasions, burns, scalds, and blisters, as well as on slow-healing or compromised skin and skin barrier dysfunction. HYPO21 Purifying Skin Spray can be applied pre- and post-surgery, including directly on open skin, areas with stitches or staples, and new surgical scars, to calm inflammation, reduce microbial load, and support the healing environment.

Rigorous microbiological testing demonstrates that HYPO21 Purifying Skin Spray meets ISO11930 standards for antimicrobial preservation efficacy, achieving a 5-log reduction within 1 minute of contact, proving it effective against gram-positive bacteria, including Staphylococcus aureus and Streptococcus pyogenes, which are associated with conditions such as impetigo, scarlet fever, and rheumatic fever. This further supports the use of HYPO21 in both preventative and active management contexts where microbial contamination or infection risk is a concern.

HYPO21 Purifying Skin Spray contributes to multiple aspects of skin recovery, healing, repairing and function. It helps control microbial activity, modulate inflammatory responses, and support tissue regeneration. It reduces erythema (redness), irritation, and itchiness while maintaining hydration and barrier stability. Its non-irritating profile allows for use on highly sensitive, inflamed, or disrupted skin without compromising tolerance.

HYPO21 Purifying Skin Spray can be applied across the face, scalp, and body. It is also suitable for use in areas such as inside the ears and nose.

For application, HYPO21 Purifying Skin Spray should be used on clean skin as a first-step intervention. The solution is sprayed directly onto the skin and allowed to dry naturally. Additional skincare products may be applied after HYPO21 has dried. It may also be used throughout the day, including over makeup to maintain hydration and microbial control. For wounds or compromised or chronic skin conditions, more frequent and liberal application is recommended without rinsing.

To maintain stability and efficacy, the product should be stored away from direct heat sources, humidity, and sunlight. Exposure to elevated temperatures or UV light may degrade the active solution and reduce performance.

Benefits of HYPO21 Purifying Skin Spray
Suitable for all skins and skin conditions. (Chronic, reactive, sensitised, compromised)
Suitable for use during pregnancy and breastfeeding.
Works to fight infection, control responses to injury, and enhance healing
Repairs and regenerates damaged skin
Part of the healthy response to injury and recovery​ to heal open wounds and poor-healing skin
Soothing and steady control over the healing process
Boosts the skin’s immune system
Kills bacteria and Staphylococcus
Suitable for the most sensitive and reactive skins
Promotes new skin growth
Reduces swelling
Activates collagen
Anti-itch, anti-bacterial, anti-inflammatory, non-irritating
Reduces redness and flaking skin
Increases hydration
It can be applied anywhere on the face, scalp, or body, including inside the ears and nose
Powerful infection control
Calms and soothes the skin
Purifies and protects the skin